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Enantioselective Recognition

Enantioselective Recognition

Enantioselective Recognition: Towards the Separation of Racemates

A new approach using chiral host compounds is used to physically discriminate between the two enantiomers of a racemate. In close collaboration with synthetic, supramolecular and combinatorial chemists, a path for the rational design of new host compounds will be suggested on the basis of molecular modelling (Monte-Carlo and molecular dynamis simulations), virtual screening and ligand binding free energies and quantum chemical calculations.

For an illustration of the impact of the research project, please follow the link.



  • Professor Jeremy D. Kilburn (University of Southampton, UK)
  • Professor Antony P. Davis (University of Bristol, UK)
  • Professor Johannes de Vries (DSM, Geleen, The Netherlands)
  • Professor Javier de Mendoza (Universidad de Autonoma de Madrid, Spain)
  • Professor Christian Roussel (Université Marseilles, France)
  • Professor Cesare Gennari (Universita' di Milano, Italy)

Support given by:
European Commission, Fifth Framework Programme „Improving the Human Research Potential and Socio-Economic Knowledge Base“